Therapeutic resistance: Ironing it out

05:58 EDT 11 Aug 2017 | Nature Publishing

Since mesenchymal-like properties in cancer cells are often associated with therapy resistance, Viswanathan et al. explored vulnerabilities of these cells. They identified an enzyme of the lipid peroxidase pathway, inhibition of which caused ferroptosis in a range of cancer types.

Original Article: Therapeutic resistance: Ironing it out


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