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Histone 1, the guardian of genome stability

20:00 EDT 17 Aug 2017 | AAAS

(Institute for Research in Biomedicine (IRB Barcelona)) Genomic instability is the main risk factor for tumor development in humans. Therefore understanding its origin and and exploring therapeutic targets is paramount.Histone 1 silences a region of the genome that causes irreparable DNA damage when translated and is lethal for the organism.

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