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Greater extent of edema associated with worse visual acuity

10:30 EDT 18 Aug 2017 | Healio

BOSTON — Patients with diabetic macular edema who experienced a greater extent of edema at 52 weeks post-ranibizumab treatment experienced worse anatomic response compared with patients with less extent of macular edema, according to a poster presented at the American Society of Retina Specialists meeting. Pravin U. Dugel, MD, and colleagues presented the findings of a post hoc analysis of 367 eyes from the Lucentis (ranibizumab, Genentech) treatment arms in the Diabetic Retinopathy Clinical Research Center Network Protocol I study. Eyes were organized into quartiles depending on the extent of their macular edema at 52 weeks. Ninety-two patients were included in quartile 1 (4 m average extent of edema), 92 were included in quartile 2 (18 m), 92 in quartile three (47 m) and 91 in quartile 4 (129 m).

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