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Exploring the Mysteries of IgG4-related Disease

08:54 EDT 18 Aug 2017 | Healio

At a 2011 symposium, clinicians and investigators officially categorized the group of immunoglobulin G4-associated diseases as an immunoglobin G4-related disease, or IgG4-RD. The group reached a consensus on the nomenclature in part because Japanese investigators had been using the term, and because the group wanted to drop the term “systemic” in association with diseases of this nature. However, more questions than answers remain about the diagnosis, pathogenesis and treatment of this relatively new group of conditions. John H. Stone, MD, MPH, professor of medicine at Harvard Medical School and director of Clinical Rheumatology and Edward Fox Chair in Medicine at the Massachusetts General Hospital (MGH), set the stage.

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