Advertisement

Topics

De novo design of a hyperstable non-natural protein–ligand complex with sub-Å accuracy

08:09 EDT 22 Aug 2017 | Nature Publishing

The first demonstration of a protein designed entirely from first principles that binds a small-molecule cofactor in a precisely predetermined orientation has now been described. The design method utilizes a remote protein core that both anchors and predisposes a flexible binding site for the desired cofactor-binding geometry.

Original Article: De novo design of a hyperstable non-natural protein–ligand complex with sub-Å accuracy

NEXT ARTICLE

More From BioPortfolio on "De novo design of a hyperstable non-natural protein–ligand complex with sub-Å accuracy"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topic

Nutrition
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...