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Type I interferons and the cytokine TNF cooperatively reprogram the macrophage epigenome to promote inflammatory activation

08:58 EDT 22 Aug 2017 | Nature Publishing

No response by an immune cell occurs in isolation but is instead the summation of multiple interacting signals. Ivashkiv and colleagues describe the epigenetic landscape that results from the integration of the inflammatory cytokines type I interferons and TNF.

Original Article: Type I interferons and the cytokine TNF cooperatively reprogram the macrophage epigenome to promote inflammatory activation

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