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Hormone Responses and Mitochondrial Functioning Adversely Impacted by Some Antiseptics

04:26 EDT 22 Aug 2017 | Genetic Engineering News

Scientists from the University of California, Davis, report that quaternary ammonium compounds (quats), which are antimicrobials found in household products, inhibit mitochondria and cellular estrogenic functions. Their study is being published online in Environmental Health Perspectives . According to the researchers, toothpastes, mouthwashes, lozenges, nasal sprays, eye drops, shampoos, lotions, intravaginal spermicidal sponges and household cleaners, all contain quats. "Disinfectants that we are putting on and in our bodies, and using in our environment, have been shown to inhibit mitochondrial energy production and the cellular estrogen response," explained biochemist Gino Cortopassi, Ph.D., in the UC Davis School of Veterinary Medicine. "This raises concern because exposure to other mitochondrial-inhibiting drugs, such as rotenone and MPTP, is associated with increased risk for Parkinson's disease." The study focused on 1,600 compounds and drugs associated with household and pharmaceutical products and examined a variety of aspects of mitochondrial functioning. The ...

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