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[Review] Infectious causes of microcephaly: epidemiology, pathogenesis, diagnosis, and management

19:54 EDT 22 Aug 2017 | The Lancet

Microcephaly is an important sign of neurological malformation and a predictor of future disability. The 2015–16 outbreak of Zika virus and congenital Zika infection brought the world's attention to links between Zika infection and microcephaly. However, Zika virus is only one of the infectious causes of microcephaly and, although the contexts in which they occur vary greatly, all are of concern. In this Review, we summarise important aspects of major congenital infections that can cause microcephaly, and describe the epidemiology, transmission, clinical features, pathogenesis, management, and long-term consequences of these infections.

Original Article: [Review] Infectious causes of microcephaly: epidemiology, pathogenesis, diagnosis, and management

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