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Scientists at Purdue University have developed a self-contained point-of-care diagnostic device that is made completely from paper, is powered by the user’s touch, and provides easy-to-read color-coded results. The self-powered, paper-based electrochemical device (SPED) has been developed for use in remote or resource-limited settings, explains Ramses V. Martinez, Ph.D., who is assistant professor of industrial and biomedical engineering at Purdue University. “SPEDs are inexpensive, lightweight, flexible, and easy to use.…We hope these devices will serve untrained people located in remote villages or military bases to test for a variety of diseases without requiring any source of electricity, clean water, or additional equipment.” The SPED format is based on microfluidic channels in which electrochemically detected colorimetric assays are carried out. The SPED structure is created in two layers. The top layer is composed of untreated cellulose paper with patterned hydrophobic domains in which the microfluidic channels wick up the ...NEXT ARTICLE
Immunoassay - ELISA
Immunoassays are quick and accurate tests to detect specific molecules. Immunoassays rely on an antibody to bind to the specific structure of a molecule. Antibodies are proteins generated by animals in response to the invasion of a foreign molecule (anti...