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Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease

08:01 EDT 24 Aug 2017 | Nature Publishing

Greg Gibson and colleagues integrate summary-level GWAS and eQTL data with RNA-seq data from a cohort of pediatric Crohn's disease and report transcriptional risk scores that identify patients who will progress to complicated disease. Their dissection of eQTL effects may be used to distinguish genes whose association with disease is through promotion or protection.

Original Article: Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease

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