Cancer Onset May Be Caused by Immune System Fighting Viruses

06:46 EDT 24 Aug 2017 | Genetic Engineering News

The development of an advanced immune system to fight off microbial pathogens is a considerable part of the evolutionary success of multicellular organisms. Yet, like most success stories there is always a flip side. New evidence from investigators at the University of Colorado (CU) Cancer Center shows how the action of various immunity-based enzymes can spill over onto the host genome when trying to fight off various viral pathogens—ultimately leading to cancer-causing DNA mutations. Findings from the new study were published recently in Viruses , in an article entitled “ Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression .” Infection with human papillomavirus (HPV) is the primary cause of cervical cancer as well as a subset of head and neck cancers worldwide. In the current study, the researchers found that a family of enzymes, called APOBEC3, may be the link between viral infection and ...

Original Article: Cancer Onset May Be Caused by Immune System Fighting Viruses


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Allergies Automimmune Disease Human Papillomavirus (HPV) Immunology Vaccine Immunology is the study of immunity and the defence mechanisms of the body. A greater understanding of immunology is needed to develop vaccines, understand ...

Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...