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Abemaciclib initial therapy improves outcome in endocrine-sensitive advanced breast cancer

20:00 EDT 8 Sep 2017 | AAAS

(European Society for Medical Oncology) The results of the MONARCH 3 trial, presented at the ESMO 2017 Congress in Madrid (1), showed that adding the cyclin-dependent kinase (CDK) 4/6 inhibitor abemaciclib to endocrine therapy improved progression-free survival compared to endocrine therapy alone in the total study population. While most women had substantial benefit from the addition of abemaciclib as initial treatment, around one-third of women may not need a CDK 4/6 inhibitor as initial treatment.

Original Article: Abemaciclib initial therapy improves outcome in endocrine-sensitive advanced breast cancer

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