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Genome mining: Digging the tunnel for chemical space

16:05 EDT 19 Sep 2017 | Nature Publishing

Genome mining reveals a new ribosomally synthesized and post-translationally modified peptide (RiPP) from Klebsiella pneumoniae. This new antibiotic inhibits bacterial ribosomes by obstructing the peptide exit tunnel, and its modular nature presents a unique opportunity for future engineering of antibacterial drugs.

Original Article: Genome mining: Digging the tunnel for chemical space

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