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Innovating on a trusted class of antibiotics to attack superbugs

22:42 EDT 25 May 2017 | Novartis

Bacterial populations evolve over time to resist antibiotics, and in a growing number of cases around the world, there are infections against which no anti-bacterial medications work at all. 

In one particularly worrisome example, certain strains of Enterobacteriaceae (a large bacterial family that includes Escherichia coli and Klebsiella pneumoniae) are resistant to powerful antibiotics called carbapenems. Almost half of hospitalized patients in the United States who get bloodstream infections from these strains will die, according to the Centers for Disease Control and ...

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