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A new blood system isn’t created from scratch—just something close to it. A single type of stem cell, a new study demonstrates, can fully repopulate the bone marrow and give rise to all the cell lineages that constitute a complete blood system. This blood-forming stem cell is distinguished by three surface markers—or rather the presence of two markers and the absence of a third. By heeding these markers, scientists may improve transplantation procedures, as well develop better gene therapy and gene editing approaches. The discovery was described November 1 in the journal Science Translational Medicine, in an article entitled, “A distinct hematopoietic stem cell population for rapid multilineage engraftment in nonhuman primates.” According to this article, CD34-positive hematopoietic stem cells (HSCs), long considered the gold standard for stem cell therapy and transplantation of stem cell–enriched grafts, do not all contribute to multilineage engraftment. In fact, few of ...NEXT ARTICLE
Track and monitor developments in stem cell research and commercial development. Follow the tabs above to read the latest global news, research, clinical trials on stem cells and follow companies active in the stem cell industry. BioPort...
Osteoporosis is a disease in which the bones become extremely porous, are subject to fracture, and heal slowly, occurring especially in women following menopause and often leading to curvature of the spine from vertebral collapse. Follow and track&n...