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Bringing natural killer cells to the tumor battlefield

19:00 EST 7 Nov 2017 | AAAS

(Luxembourg Institute of Health) By studying melanoma, a highly malignant form of skin cancer, Dr Bassam Janji's research team at the Luxembourg Institute of Health (LIH) has revealed a mechanism by which the immunosuppressive environment can be switched to an immunosupportive one. They found that if autophagy -- the intracellular recycling process -- is blocked in tumor cells, they produce cytokines that attract NK cells. The massive recruitment of NK cells allows killing cancer cells and lets the tumors shrink.

Original Article: Bringing natural killer cells to the tumor battlefield

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