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Novartis’ VEGF inhibitor demonstrates clinically relevant anatomic, visual gains

11:00 EST 11 Nov 2017 | Healio

Pravin Dugel
NEW ORLEANS — Novartis’ first-in-kind molecule brolucizumab achieved clinically relevant anatomic and visual acuity gains in patients with age-related macular degeneration with every-12-week dosing, according to a speaker.
Two dosages of the single-chain antibody fragment VEGF inhibitor were compared with Eylea (aflibercept, Regeneron) in two phase 3 trials, HAWK and HARRIER, Pravin U. Dugel, MD, said at Retina Subspecialty Day preceding the American Academy of Ophthalmology meeting, where he reported 48-week results.
Not only did brolucizumab meet the primary endpoint

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