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Stable Fluorophores for Optical-Guided Imaging in Surgical Interventions

19:00 EST 1 Mar 2017 | NIH

Researchers in the NCI Chemical Biology Laboratory developed an improved class of heptamethine cyanines fluorophore dyes useful for imaging applications in the near-IR range (750-850 nm). A new chemical reaction provides easy access to novel molecules with improved properties. Specifically, these dyes display greater resistance to thiol nucleophiles, and are more robust while maintaining excellent optical properties.

Original Article: Stable Fluorophores for Optical-Guided Imaging in Surgical Interventions

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