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Novartis to Develop Treatments for Eye, Blood Disorders Using Homology's AAV Gene-Editing Platform

05:50 EST 13 Nov 2017 | Genetic Engineering News

Novartis will use Homology Medicines’ proprietary adeno-associated virus (AAV) gene-editing platform technology to develop new treatments for select ophthalmic targets and a hemoglobinopathy disease, the companies said today. Under a research and development collaboration whose value was not disclosed, Novartis will work with Homology to adapt and refine its gene-editing technology for the treatment of a blood disorder and certain eye diseases, all unspecified. Researchers from Novartis and Homology will work to advance treatment candidates toward clinical testing, the companies said. Novartis said the collaboration is designed to accelerate an initiative at its Novartis Institutes for BioMedical Research (NIBR) that engages researchers companywide who are involved in projects with the genetic reprogramming of cells. Homology’s AAV technology may aid their work, Novartis reasons: “It is our hope that this collaboration will help advance our cell and gene therapy initiative,” Susan Stevenson, Ph.D., an executive director at ...

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