Promising new CAR-T therapy able to target T-cell lymphoma

05:38 EST 15 Nov 2017 | Pharmafile

The CAR-T space has progressed rapidly over the last few years, culminating in FDA approvals for Novartis and Gilead to treat B-cell lymphomas; however, work conducted by Autolus has potentially opened a new therapeutic pathway for the treatment of T-cell lymphoma.

Therapies for T-cell lymphoma are notoriously difficult to develop because any treatment targeting T cells damages the body’s key line of defence against illness. On top of this, the T cell version of lymphoma is far more aggressive than the B-cell version, though more infrequently found.

Image caption: 
Dr Martin Pule, CSO of Autolus, on whose work the CAR T therapy is based IMAGE: UCL

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Original Article: Promising new CAR-T therapy able to target T-cell lymphoma


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