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CRISPR/Cas3 Platform Developer Locus Biosciences Raises $19M in Series A Financing

05:22 EST 16 Nov 2017 | Genetic Engineering News

Locus Biosciences, developer of a next-generation CRISPR /Cas platform for precision antimicrobials, has closed $19 million in Series A funding designed to fund the company through filing its first Investigational New Drug (IND), as well as a subsequent first-in-human trial. A spinout of North Carolina State University (NCSU) founded in 2015, Locus Biosciences designs and creates novel CRISPR RNAs or “smart bombs” designed to kill antibiotic-resistant “superbugs” by irreversibly destroying the bacterial DNA. Locus says it is the only company that uses CRISPR/Cas3 to kill targeted pathogens, such as Clostridium difficile, Pseudomonas aeruginosa , and Enterobacteriaceae—rather than with Cas9 as used by Paris-based Eligo Bioscience, which on September 26 said it closed on $20 million in Series A financing from Khosla Ventures and Seventure Partners, including a $2 million award from the Worldwide Innovation Challenge. As a result, Locus steers clear of the bitter legal battle ...

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