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Novel Continuous Cell Culture Method for Adherent Cells: Is it Useful?

05:50 EST 21 Nov 2017 | Genetic Engineering News

A new cell culture method for adherent cells—touted as a continuous upstream manufacturing technique suited specifically for cell-based therapies—was recently announced . The technique relies on a special coating applied to surfaces where adherent cells attach. The Newcastle University study describing the approach was published in ACS Applied Materials & Interfaces. The coating is said to be capable of controlling the attachment and proliferation of cells, and it reportedly also allows the cells (in this case, human corneal stromal cells) to self-detach from culture. This is a departure from current cell-detachment methods, wherein cells are typically removed from a growth surface with the help of chemicals. Because the cells grow in a sheet and slough away from the surface independently, surface area for a new layer of cells to form is continuously available. GEN spoke to John Bonham-Carter (who was not involved with the study), director of ...

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