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The complement activation product C4d can be used to monitor patients with systemic lupus erythematosus, as these levels correlate with disease activity and could potentially predict lupus nephritis flares, according to findings published in Arthritis Research and Care.
“Low serum levels of complement components C3 and C4 have been used for over 50 years to indicate lupus activity and are included in the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI),” Myriam Martin, PhD, of Lund University, in Malmö, Sweden, and colleagues wrote. “A variety of other
Original Article: C4d levels predict lupus nephritis flares, help inform treatmentNEXT ARTICLE
Lupus is a complex and poorly understood condition that affects many parts of the body and causes symptoms ranging from mild to life-threatening. There are several types of lupus. The main types are: discoid lupus erythematosus drug-induced lu...
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