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For the first time, a real pathogen has instigated a real disease process in an artificial organ, and scientists are really, really pleased. As far as scientists are concerned, the whole point of an artificial organ—in this case, a liver-on-a-chip platform—is to simulate a real organ’s physiology, and that includes pathophysiology. By using an artificial liver to model the interactions between human tissue and an infectious agent—in this case, hepatitis B—scientists based at Imperial College London have opened a new front in disease research and, potentially, the development of new drugs. “This is the first time that organ-on-a-chip technology has been used to test viral infections,” said Marcus Dorner, Ph.D., a researcher at Imperial's School of Public Health. “Our work represents the next frontier in the use of this technology. We hope it will ultimately drive down the cost and time associated with clinical trials, which will benefit ...
Original Article: Hepatitis B Infects Organ-on-a-Chip PlatformNEXT ARTICLE
Hepatology is the study of liver, gallbladder, biliary tree, and pancreas, and diseases associated with them. This includes viral hepatitis, alcohol damage, cirrhosis and cancer. As modern lifestyles change, with alcoholism and cancer becoming more promi...
Antiretroviral Therapy Clostridium Difficile Ebola HIV & AIDS Infectious Diseases Influenza Malaria Measles Sepsis Swine Flu Tropical Medicine Tuberculosis Infectious diseases are caused by pathogenic...
Astroesophageal Reflux Disease (GERD) Barrett's Esophagus Celiac Disease Cholesterol Crohn's Disease Gastroenterology Hepatitis Hepatology Irritable Bowel Syndrome (IBS) Pancreatitis Peptic Ulcer Disease...