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Targeting pathway may reduce cocaine's cardiovascular harms

19:00 EST 25 Feb 2018 | AAAS

(American Heart Association) Cocaine in mice increased levels of reactive oxygen species, molecules known to cause cardiovascular disease. Cocaine acts through microRNA (miR)-30c-5p, which leads to excess level of reactive oxygen species. Preventing activation of miR-30c-5p suppressed cocaine's harmful effects to the cardiovascular system, suggesting a potential treatment for cocaine-related cardiovascular disease.

Original Article: Targeting pathway may reduce cocaine's cardiovascular harms

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