University Hospitals system adopts Magseed marker as standard of care for localisation of impalpable breast lesions

04:52 EDT 14 Mar 2018 | Zyme Communications

Another top 30 cancer centre looks to standardise use of Magseed to improve patient experience

Cambridge, UK and Cleveland, OH, 13th March 2018: Endomag, the surgical guidance company, announced today that University Hospitals (UH), one of the leading healthcare systems in the US, providing high-quality, patient-centred cancer care at locations throughout Northeast Ohio, has expanded the use of its Magseed® marker technology at more sites within the UH system. Magseed offers a simpler and more efficient system for localisation of breast lesions than traditional hookwire techniques, improving patient experience and surgery scheduling. UH Seidman Cancer Center, UH Ahuja and UH Cleveland Medical campuses have been offering Magseed as the standard of care, carrying out over 450 successful procedures in the last 12 months. UH is now making Magseed available at other facilities to enhance the standard of breast care in the UH system.

The Magseed marker is the world’s first minimally-invasive surgical guidance system indicated to mark any soft tissue and long-term implantation. Magseed is a small, non-radioactive seed, smaller than a grain of rice, that helps surgeons locate impalpable breast cancer. Traditional hookwire methods require an additional visit to Radiology on the day of surgery, which can lead to delays in the OR. Furthermore, these techniques are often inefficient, invasive, inconvenient, and can be uncomfortable for the patient.

UH is dedicated to providing the highest quality of treatment for its patients and consistently strive for outstanding clinical outcomes. UH aims to maintain a positive experience for the patient from mammogram through to diagnosis and treatment, while supporting its physicians by supplying the most advanced diagnostic tools to ensure that the clinical care they provide is considered and delivered with confidence. UH started using Magseed at UH Seidman Cancer Center, UH Cleveland Medical Center and UH Ahuja Medical Center in March 2017 and is now making this technique available at more sites across the UH system, allowing all patients to experience the benefits.

Dr Donna Plecha, Director, Breast Imaging, Mammography at UH Cleveland Medical Center and Director, Breast Imaging at UH Seidman Cancer Center, said: ‘We’ve been using Magseed for nearly a year and can already see efficiency improvements in Radiology, and a better experience for our patients. Magseed allows us to mark the tumour at the same time as their pre-operative surgical clinic appointment, saving them an additional visit to the hospital, and by expanding Magseed availability across the UH system, we allow our patients the freedom to choose the UH facility that’s most convenient for them.’

Jenna Hundorfean, Manager, Breast Health Services at UH Cleveland Medical Center, said: ‘The start time in the OR sets the tone for the day. Wires often result in delays in Radiology, placing pressure on staff to keep successive surgeries on schedule. With Magseed, the Radiology department isn’t under pressure to get patients to the operating theatre in the morning, meaning we can start on time. Magseed decouples radiology and surgery, allowing the surgical day schedule to run independently of radiology procedures. Each surgical procedure also takes less time, resulting in increased efficiency, productivity and an improved experience for our patients.’

Dr Jill Dietz, Director of Breast Center Operations and Associate Professor of Surgery at UH Cleveland Medical Center, said: ‘Magseed offers significant advantages for both patient and surgeon. I am confident that it will enable UH to achieve its objectives, to build trusting patient-physician partnerships and improve clinical outcomes by providing the best possible care available. Not only is Magseed more likely to remove all the cancerous tissue, reducing the need for additional surgeries but in some patients, there is the option of choosing where to place the incision, allowing for a better cosmetic outcome.’

Fig 1: The Magseed deployment needle (18-gauge) is the same as used in thousands of radioactive seed deployments

Fig 2: Magseed can be placed in any soft tissue without a restriction on implantation time

Fig 3: Magseed is 60% smaller than other non-radioactive lesion localisation markers

About Endomag

Endomag’s mission is to improve the standard of cancer care for everyone, everywhere, by providing more accurate, convenient and less-expensive solutions for diagnosis and treatment.

Endomag has developed a minimally-invasive surgical guidance system, which can locate early-stage and impalpable tumours, and help determine whether the cancer has spread. The system uses magnetic field technology, providing a safer, more comfortable and efficient option, over alternative techniques. The system has been used in over 30,000 procedures across 300 hospitals in 30 countries and is the subject of 12 clinical publications, all confirming its efficacy compared with current standards.

About University Hospitals

Founded in 1866, University Hospitals serves the needs of patients through an integrated network of 18 hospitals, more than 40 outpatient health centers and 200 physician offices in 15 counties throughout northern Ohio. The system’s flagship academic medical center, University Hospitals Cleveland Medical Center, located on a 35-acre campus in Cleveland’s University Circle, is affiliated with Case Western Reserve University School of Medicine. The main campus also includes University Hospitals Rainbow Babies & Children's Hospital, ranked among the top children’s hospitals in the nation; University Hospitals MacDonald Women's Hospital, Ohio's only hospital for women; and University Hospitals Seidman Cancer Center, part of the NCI-designated Case Comprehensive Cancer Center. UH is home to some of the most prestigious clinical and research programs in the nation, including cancer, pediatrics, women's health, orthopedics, radiology, neuroscience, cardiology and cardiovascular surgery, digestive health, transplantation and urology. UH Cleveland Medical Center is perennially among the highest performers in national ranking surveys, including “America’s Best Hospitals” from U.S. News & World Report. UH is also home to Harrington Discovery Institute at University Hospitals – part of The Harrington Project for Discovery & Development. UH is one of the largest employers in Northeast Ohio with 26,000 employees. Follow UH on Facebook @UniversityHospitals and Twitter @UHhospitals. For more information, go to

About breast tumour localisation

Breast cancer is the most common form of cancer in women, with 1.7 million new cases of breast cancer globally every year and is expected to double by 2030. Due to a rise in national screening programmes and an increase in public awareness, breast cancer is being diagnosed and treated at an earlier stage meaning that the tumours are smaller, less defined and harder to feel, with as many as 50% of all breast tumours impalpable at the time of diagnosis. In these cases, a technique called wire localisation is typically used by surgeons to locate the tumour.

Although widely used, wire localisation commonly causes complications. On average 1 in every 4 breast wire localisations result in cancerous tissue being left behind and requiring additional treatment, often because the wire has become dislodged between when it was implanted and when it was removed during surgery. This often means the patient requires an additional surgical procedure to remove the residual tumour and can result in the need for a mastectomy. Additionally, there is a risk of infection due to the wire protruding from the skin, so the placement of the wire must be done on the same day as surgery. These issues result in unnecessary anxiety for patients, delays to the surgical lists and fewer patients being treated as a consequence.

The Radioactive seed technique is an improvement on wire localisations and involves placement of small radioactive (iodine-125) metal seed within the breast lesion, enabling precise localisation of cancerous tissue up to 5 days ahead of surgery. The use of radioactive components during breast surgery is subject to strict nuclear regulatory requirements and close monitoring/tracking procedures to ensure that the seeds handled appropriately and are not lost during operations.

Radar localisation attempts to improve on radioactive seed localisation by using infrared and radar to detect a reflector that is placed at the tumour site ahead of surgery. However, the reflector is much larger (>12mm long) than radioactive or magnetic seeds and is prone to deactivation during placement or during the surgical procedure from electrocautery. Also, the infrared from the OR lights or surgeon headlamps can interfere with the signal, all of which can compromise the accuracy of the surgery.

About Magseed

Magseed is smaller than a grain of rice and can be implanted into soft tissue without any restrictions on the time it’s implanted, allowing the patient to return home ahead of surgery. Once implanted, the seed can’t be damaged and is not easily dislodged so patients aren’t restricted in movement or activity. On the day of surgery, patients aren’t subjected to a localisation procedure and can instead go straight to the OR. During surgery, the seed is detected with the Sentimag® probe to guide accurate removal all of the tumour and maximising the amount of healthy tissue left behind. Unlike radioactive alternatives that involve strict regulatory oversight and complex logistics, the Magseed technique can be widely adopted by any hospital, regardless of size

Zyme Communications Lorna Cuddon Tel: +44 (0)7811 996 942 Email: NEXT ARTICLE

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