Molecular Devices Discusses Human iPSC-based Neural Spheroid Platform for High Throughput Drug Screening in Educational Webinar

09:00 EDT 14 Mar 2018 | PR Web

In this webinar, which LabRoots will host April 17, attendees will gain a better understanding of the applications of microBrain 3D Assay Ready for high throughput drug screening.

Yorba Linda, CA (PRWEB) March 14, 2018

Many nations around the globe have made concerted efforts to develop research and funding initiatives that focus on understanding the brain in health. Locally, researchers are focused on obtaining 3D brain organoids in an attempt to better recapitulate neuro development and function in vitro. However, current protocols lead to variable organoid size and function, making the use of these powerful tools impractical in drug screening scenarios.

During this webinar, the speakers will describe StemoniX® microBrain® 3D Assay Ready, a highly homogenous human induced Pluripotent Stem Cell (hiPSC)-derived cortical spheroid screening platform in a 384-well format. Each well contains a single uniformly sized spheroid, with a fully developed foundation of cortical neurons and astrocytes co-matured from a single donor source.

microBrain cortical spheroids present highly synchronized, quantifiable, robust, and uniform spontaneous calcium oscillations, which can be measured in kinetic high throughput screening (HTS) plate readers, such as the FLIPR Tetra® High-Throughput Cellular Screening System, and, at the cellular level, with high content imaging systems, such as the ImageXpress® Micro Confocal High-Content Imaging System. The calcium signal can be reproducibly modified with excitatory and inhibitory neuromodulators, confirming the presence of a functionally integrated glutamatergic and GABAergic circuitry.

Through this webinar, which is sponsored by Molecular Devices, participants will learn the key characteristics of microBrain 3D Assay Ready spheroids. They will also understand how microBrain 3D Assay Ready is delivered to the customer ready to use, integrating easily into their high throughput screening platforms.

Participants will hear from three speakers during this presentation Dr. Cassiano Carromeu Senior Scientist at StemoniX
; Dr. Grischa Chandy, SeniorPproduct Manager of Cellular Imaging at Molecular Devices; and
Dr. Oksana Sirenko, Senior Research Scientist with Molecular Devices.

LabRoots will host the event April 17, 2018; the webinar will begin at 8 a.m. PDT, 11 a.m. EDT. To learn more about this event and the speakers, discover the continuing education credits that will be offered, or to register for free, click here.

About Molecular Devices, LLC
Molecular Devices is one of the world's leading providers of high-performance bioanalytical measurement systems, software and consumables for life science research, pharmaceutical and biotherapeutic development. Included within a broad product portfolio are platforms for high-throughput screening, genomic and cellular analysis, colony selection and microplate detection. These leading-edge products enable scientists to improve productivity and effectiveness, ultimately accelerating research and the discovery of new therapeutics.

Molecular Devices is committed to the continual development of innovative solutions for life science applications. The company is headquartered in Silicon Valley, California with offices around the globe.

For more information, visit:

About LabRoots
LabRoots is the leading scientific social networking website, which provides daily scientific trending news, as well as produces educational virtual events and webinars, on the latest discoveries and advancements in science. Contributing to the advancement of science through content sharing capabilities, LabRoots is a powerful advocate in amplifying global networks and communities. Founded in 2008, LabRoots emphasizes digital innovation in scientific collaboration and learning, and is a primary source for current scientific news, webinars, virtual conferences, and more. LabRoots has grown into the world’s largest series of virtual events within the Life Sciences and Clinical Diagnostics community.

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