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Huntingtin Huntington Disease Protein or HTT pipeline Target constitutes close to 15 molecules. Out of which approximately 13 molecules are developed by companies and remaining by the universities/institutes.
The latest report Huntingtin Pipeline Review, H1 2018, outlays comprehensive information on the Huntingtin Huntington Disease Protein or HTT targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action MoA, route of administration RoA and molecule type.
Huntingtin Huntington Disease Protein or HTT Huntingtin protein is an encoded by the huntingtin gene, also called the HTT or HD Huntington disease gene. Huntingtin up regulates the expression of brain derived neurotrophic factor BDNF at the transcription level. Huntingtin is primarily associated with vesicles and microtubules.
These indicate an important role in cytoskeletal anchoring or transport of mitochondria. The Htt protein is involved in vesicle trafficking as it interacts with HIP1 to mediate endocytosis. Huntingtin also plays an important role in the establishment in epithelial polarity through its interaction with RAB11A. The molecules developed by companies in Phase II, Preclinical and Discovery stages are 3, 7 and 3 respectively.
Similarly, the universities portfolio in Preclinical and Discovery stages comprises 1 and 1 molecules, respectively. Report covers products from therapy areas Central Nervous System and Genetic Disorders which include indications Huntington Disease, Alzheimer's Disease, Kennedy's Disease Spinal and Bulbar Muscular Atrophy and Spinocerebellar Ataxia SCA.
Furthermore, this report also reviews key players involved in Huntingtin Huntington Disease Protein or HTT targeted therapeutics development with respective active and dormant or discontinued projects. Driven by data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industryspecific third party sources.
Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.
The report provides a snapshot of the global therapeutic landscape for Huntingtin Huntington Disease Protein or HTT
The report reviews Huntingtin Huntington Disease Protein or HTT targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industryspecific sources
The report covers pipeline products based on various stages of development ranging from preregistration till discovery and undisclosed stages
The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, RD brief, licensing and collaboration details other developmental activities
The report reviews key players involved in Huntingtin Huntington Disease Protein or HTT targeted therapeutics and enlists all their major and minor projects
The report assesses Huntingtin Huntington Disease Protein or HTT targeted therapeutics based on mechanism of action MoA, route of administration RoA and molecule type
The report summarizes all the dormant and discontinued pipeline projects
The report reviews latest news and deals related to Huntingtin Huntington Disease Protein or HTT targeted therapeutics
Reasons to buy
Gain strategically significant competitor information, analysis, and insights to formulate effective RD strategies
Identify emerging players with potentially strong product portfolio and create effective counterstrategies to gain competitive advantage
Identify and understand the targeted therapy areas and indications for Huntingtin Huntington Disease Protein or HTT
Identify the use of drugs for target identification and drug repurposing
Identify potential new clients or partners in the target demographic
Develop strategic initiatives by understanding the focus areas of leading companies
Plan mergers and acquisitions effectively by identifying key players and it's most promising pipeline therapeutics
Devise corrective measures for pipeline projects by understanding Huntingtin Huntington Disease Protein or HTT development landscape
Develop and design inlicensing and outlicensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scopeNEXT ARTICLE
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