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Human Brain Organoids Thrive in Mouse Brains

07:15 EDT 17 Apr 2018 | Genetic Engineering News

Brain organoids, stem-cell-based models of real brain tissue, have moved into petri dishes and test tubes, but they have never quite felt themselves at home. The organoids’ cells don’t divide or diversify very much, and they don’t live very long, limiting their potential to recapitulate neurological diseases for the benefit of medical researchers and drug developers. Organoids may thrive, however, if they settle in more physiological environs—blood vessel–rich regions of mouse brain.

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