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WASHINGTON — A nanomicellar formulation of cyclosporine A was well tolerated with a low rate of ocular adverse events or instillation site pain, according to a study presented here.
“The OTX-101 formulation was found in this clinical trial to be superior to vehicle in both increasing tear production and improving corneal and conjunctival staining after 12 weeks of therapy in patients with keratoconjunctivitis sicca,” Jodi Luchs, MD, FACS, said at the American Society of Cataract and Refractive Surgery meeting.
Luchs reported the results of a phase 3 study assessing the ocular
Pain is defined by the International Association for the Study of Pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage”. Some illnesses can be excruci...
In a clinical trial or interventional study, participants receive specific interventions according to the research plan or protocol created by the investigators. These interventions may be medical products, such as drugs or devices; procedures; or change...
Ophthalmology is the branch of medicine that is devoted to the study and treatment of eye diseases. As well as mild visual defects correctable by lenses, ophthalmology is concerned with glaucoma, uveitis and other serious conditions affecting the eye, ...