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Study reports possible novel method for stopping untreatable pediatric brain cancers

20:00 EDT 16 Apr 2018 | AAAS

(Cincinnati Children's Hospital Medical Center) Researchers used an experimental molecular therapy in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer and now propose advancing the treatment to clinical testing in children. Scientists report in the journal Molecular Cancer Therapeutics testing the small molecule 6-thio-2'deoxyguanosine (6-thio-dG) in brain cancer stem cells derived from tumor cells donated by patients. Researchers also tested the treatment in humanized mouse models of pediatric brain cancer.

Original Article: Study reports possible novel method for stopping untreatable pediatric brain cancers

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