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Scientists knew the PDK1 signaling pathway was active in metastasizing cancer cells, but no one knew why. New research has found for the first time that the PDK1 pathway regulates the formation of a three-protein core complex that facilitates purine biosynthesis. Further work aims to map all the protein complexes and signaling pathways they regulate in cancer cells, which would open doors to new ways of disrupting or even preventing metastasis.
Original Article: New molecular mechanism likely involved in cancer metastasisNEXT ARTICLE
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Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...