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The Entropic Term is Laughing At Us

08:38 EDT 11 Jul 2018 | Science

There are plenty of things to optimize in a med-chem project other than binding affinity. But if you don’t have at least some level of binding, you may not have a med-chem project. And while from the outside, you might think that understanding how and why compound A binds to a given target while compound

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