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Cell Lines Expressing Nuclear and/or Mitochondrial RNase H1

19:00 EST 5 Nov 2012 | NIH

RNase H1 has been shown to remove RNA/DNA hybrids and either too much or too little enzyme can lead to undesirable effects such as deletions of DNA. The gene encoding RNase H1 in mammalian cells produces two forms of the protein. One is targeted to the nucleus of the cell and the other to the mitochondrial organelle.

Original Article: Cell Lines Expressing Nuclear and/or Mitochondrial RNase H1

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