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Quantitative in vivo Methods to Estimate the Conduction Time of Nerve Impulses in the Brain

20:00 EDT 23 May 2012 | NIH

The axon diameter distribution (ADD) is an important anatomical feature of nerve fascicles both in normal and abnormal development. Axon diameter directly affects nerve function. It is well known that in myelinated axons, the conduction velocity is directly proportional to axon diameter. Moreover, it is hypothesized that in amyotrophic lateral sclerosis (ALS) large diameter axons are damaged selectively, while in autism, small-diameter axons are over-expressed.

Original Article: Quantitative in vivo Methods to Estimate the Conduction Time of Nerve Impulses in the Brain

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