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New research effort to understand role of APOE mutation in Alzheimer's disease

20:00 EDT 12 Jul 2018 | AAAS

(Jackson Laboratory) Inheriting a specific genetic variant, APOEε4, is linked with 15-20 percent percent rise in risk of developing Alzheimer's, with at least 20 other genes implicated. The National Institute on Aging awarded a five-year grant totaling $4.2 million to Jackson Lab to study how APOEε4 risk depends on other genes, in mice with a wide variety of genetic backgrounds.

Original Article: New research effort to understand role of APOE mutation in Alzheimer's disease

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