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Stems Cells Used as Delivery Truck for Brain Cancer Drugs

06:10 EDT 30 Aug 2018 | Genetic Engineering News

Common brain cancers in children, such as medulloblastoma, have been notoriously difficult to treat therapeutically, with traditional interventions reliant on inefficient surgical techniques to remove the bulk of the cancerous tissue. However now, new data from the University of North Carolina Lineberger Comprehensive Cancer Center and UNC Eshelman School of Pharmacy may lead to a more effective way to treat these aggressive tumors. Findings from the new study—published today in PLOS ONE through an article entitled “ Intra-cavity stem cell therapy inhibits tumor progression in a novel murine model of medulloblastoma surgical resection ”—demonstrates how cancer-hunting stem cells can track down and deliver a drug to destroy medulloblastoma cells hiding after surgery. The cells are like a FedEx truck that will get you to a particular location, and (deliver) potent cytotoxic agents directly into the tumor, explained senior study investigator Shawn Hingtgen, Ph.D., an assistant professor in the ...

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