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Checkpoint-targeting immunotherapies get a helping hand from natural killer cells

20:00 EDT 9 Sep 2018 | AAAS

(JCI Journals) Immunotherapies targeting the immune checkpoint receptor PD-1 and its ligand, PD-L1, have been shown to successfully activate T cells against certain cancers, but their efficacy varies between cancer types and between individual patients. An article published in this week's issue of the JCI describes an important role for natural killer in PD-1/PD-L1-targeting immunotherapy, a discovery that may help scientists develop more powerful immune-targeting anti-cancer treatments.

Original Article: Checkpoint-targeting immunotherapies get a helping hand from natural killer cells

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