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This KOL Insight briefing focuses on KOL opinions of the safety of JAK inhibitors in rheumatoid arthritis RA.
The briefing includes analysis of KOL opinion on the following topic areas
Baricitinib safety profile with regards to cardiovascular signal
Tofacitinib safety profile with regards to cardiovascular signal
Upadacitinib safety profile with regards to cardiovascular signal
Filgotinib safety profile with regards to cardiovascular signal
Most favorable JAK inhibitor with regards to cardiovascular safety
Extent in which thromboembolic events is a class effect across all JAK inhibitors
Additional studies / actions required to mitigate concerns around cardiovascular safety in the JAK inhibitors class
Majority of KOLs acknowledged that there was a CV signal with baricitinib in RA, although many flagged this was not necessarily a concern
While KOLs generally had a positive opinion of tofacitinib's CV risk profile, many stated the need for more safety data
Most KOLs highlighted the need for additional data before drawing conclusions regarding upadacitinib's CV safety profile.
The insight briefing is based on Sociable Pharma's analysis of primary research with our RA key opinion leaders KOLs
In total, we conducted interviews with 10 KOLs: Five Europebased five USbased
Interviews conducted in December 2017
KOL data is analyzed to produce: Charts summarizing KOL opinions
Chart callouts of key information details
Summary of KOL reporting trends
Insight from Sociable Pharma's analysts.
Reasons to buy
Combines Qualitative semiquantitative insight from key opinion leaders on "Cardiovascular safety profile of JAK inhibitors in Rheumatoid Arthritis".
Includes insight recommendations from our diseasespecific healthcare analysts
Utilizes independent expert viewpoints to validate the impact of new clinical data emerging trends on management of rheumatoid arthritis
Provides costeffective support for your advisory boards, with topics acting as a catalyst for further expert discussion.NEXT ARTICLE
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