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Prof Marion Subklewe speaks to ecancer at ASH 2018 about the phase 1 study into AMG330, an anti-CD33 bispecific T-Cell engager antibody construct, in relapsed/refractory AML. She explains that the issue with the T cell antibody construct is cytokine...NEXT ARTICLE
An antibody is a protein produced by the body's immune system when it detects harmful substances, called antigens. Examples of antigens include microorganisms (such as bacteria, fungi, parasites, and viruses) and chemicals. Antibodies may be produc...
Cytokine Tumour Necrosis Factor (TNF)
TNF is a compound that is classified as a cytokine which plays a central role in the cellular mechanisms of apoptosis or cell death. However, there are a number of different kinds of TNF, just under twenty, but the family of molecules have very similar a...