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Activating tooth regeneration in mice

19:00 EST 19 Feb 2019 | AAAS

(King's College London) Most reptiles and fish have multiple sets of teeth during their lifetime. However, most mammals, such as humans, have only one set of replacement teeth and some mammals, like mice, have only a single set with no replacement. This diversity raises both evolutionary questions -- how did different tooth replacement strategies evolve? -- and developmental ones -- which mechanisms prevent replacement teeth in animals that lost them?

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