Topics

Epicutaneous Immunotherapy vs Placebo for Peanut Protein Ingestion Among Peanut-Allergic Children

19:00 EST 21 Feb 2019 | JAMA

Allergy to peanuts is relatively common, and the reactions to exposure can be severe, resulting in anaphylaxis and even death. Avoiding ingestion is the traditional recommendation. However, avoiding peanuts is often difficult because they can be hidden in prepared foods or contaminate foods during preparation or processing. Therefore, attention has turned to prevention of peanut allergy. Approaches that have been studied among high-risk children include ingestion of peanut protein at a young age to reduce the risk of developing peanut allergy and desensitization with oral or sublingual immunotherapy. Another approach is epicutaneous immunotherapy—using skin patches containing peanut protein. The theoretical advantages of this approach include ease of use and a lower risk of allergic reactions. Because of the difficulty in managing peanut allergy, the potential severe consequences of a reaction, and the lack of available treatments, the editors considered the phase 3 study of the “peanut patch” reported in this issue—providing data on the effectiveness and adverse events compared with a placebo patch—to be important.

Original Article: Epicutaneous Immunotherapy vs Placebo for Peanut Protein Ingestion Among Peanut-Allergic Children

NEXT ARTICLE

More From BioPortfolio on "Epicutaneous Immunotherapy vs Placebo for Peanut Protein Ingestion Among Peanut-Allergic Children"

Quick Search

Relevant Topics

Allergies
The term allergy is used to describe a response, within the body, to a substance, which is not necessarily harmful in itself, but results in an immune response and a reaction that causes symptoms and disease in a predisposed person, which in turn can cau...

Pediatrics
Pediatrics is the general medicine of childhood. Because of the developmental processes (psychological and physical) of childhood, the involvement of parents, and the social management of conditions at home and at school, pediatrics is a specialty. With ...