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Tomocube 3D Microscope Captures Key Cellular Dynamic Responses to Parkinson Drug Treatment

05:27 EDT 26 Mar 2019 | Lab Bulletin

Quantitative characterization of SH-SY5Y cells in the presence of MPP+. Red, Apoptotic cells; Green, Dividing cells; Blue, Normal cells

Holotomography (HT) technology enables rapid, high-resolution, label-free, quantitative 3D imaging of healthy and dying cells. Although Parkinson’s disease (PD) is a relatively common neurodegenerative disease, therapeutic treatments are still limited due to its complex pathophysiology. Now, a Korean research team led by Su-A Yang and Jonghee Yoon of the KAIST Institute of Health Science and Technology in Daejeon, has demonstrated...

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Parkinson's Disease
Parkinson's is a progressive neurological condition, affecting one person in every 500, 95% of which are over 40. It is caused by degeneration of more than 70% of the substantia nigra, which depletes the dopamine (the neurotransmitter involved in pro...