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In basket trials, cancers with differing histologies are pooled and the common element is a singular genetic mutation or protein alteration. The trial tests a drug that targets a common biologic process. This ability to assess numerous cancer types with one biomarker has created a paradigm shift in oncology trials. In this free webinar, learn how to design and execute basket trials for oncology studies from an expert in cancer trials.
TORONTO (PRWEB) April 17, 2019
Clinical trials of new cancer treatments have historically focused on disease type by tumor location: breast cancer, brain tumor, colon cancer and so on. With advances in medical oncology and genomic characterization of tumors, we are now able to test new therapies that target a single biomarker in multiple tumor types by conducting “basket trials.” This ability has created a paradigm shift in oncology trials.
In basket trials, cancers with differing histologies are pooled and the common element is a singular genetic mutation or protein alteration. The biomarker may be a protein or a DNA alteration. The tumors of interest are grouped in baskets for the analysis. The basket trial tests a drug that targets a common biologic process. Because of the different tumors involved, the recruiting physicians may represent many different areas of specialization.
For more information or to register for this event, visit Oncology Clinical Trials – The Paradigm Shift of Basket Trials: Key Considerations.
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For the original version on PRWeb visit: https://www.prweb.com/releases/oncology_clinical_trials_the_paradigm_shift_of_basket_trials_key_considerations_upcoming_webinar_hosted_by_xtalks/prweb16249240.htmNEXT ARTICLE
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