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Scientists have used CRISPR-Cas9 technology to identify potential new targets for glioblastoma, the most common type of primary brain tumor in adults. The approach used genome editing to effectively reverse engineer patient-derived, tumor-propagating glioblastoma stem cells gene by gene, and identify genes that are essential for tumor growth. The studies provided new insights into the basis of glioblastoma resistance to temozolomide chemotherapy, and potential strategies for combination treatment.
Original Article: CRISPR Screens Identify New Glioblastoma Targets and Resistance GenesNEXT ARTICLE
Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...
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