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Modifying Natural Products

10:15 EDT 1 May 2019 | Science

Here’s a thorough review of a topic that combines complex drug development issues with complex chemistry: trying to optimize the structures of natural products so that they can be more effective drugs. There are detailed looks at examples like the tetracyclines, the polyene macrolides, pactamycin, geldanamycin, and the thiostrepton-like peptides, along with shorter coverage of

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