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Batavia Biosciences partners with the University of Tokyo to develop a vector-based vaccine ...

02:00 EDT 14 May 2019 | BioMedReports - Blog

Leiden, the Netherlands, May 14, 2019 – Batavia Biosciences announced today that it will work together in a consortium including the European Vaccine Initiative and Stanford University, icddr,b, and headed by the University of Tokyo, to develop an epidemic preparedness vaccine against the Nipah virus. For this purpose, the University of Tokyo received a $31 million grant from the Coalition for Epidemic Preparedness (CEPI) – which finances and coordinates the development of vaccines against infectious disease –  to use its measles vector technology to develop and stockpile a Nipah vaccine.

There is currently no effective medical countermeasure against the Nipah virus and therefore it is listed as one of the main priorities of the WHO. The virus is prevalent in Southeast Asia and the Indian subcontinent and causes illness ranging from fever and headache, to acute respiratory illness, and even fatal encephalitis. The Nipah virus is also known to cause severe disease in domestic pigs, resulting in significant regional economic loss. “The need for effective medical intervention strategies against this virus is huge and therefore, we are very excited to be working with the consortium in developing a Nipah vaccine", says Dr. Menzo Havenga, President & CEO of Batavia Biosciences. 

As partner in the consortium, Batavia will receive $9.6 million to deliver a low-cost manufacturing process that can be easily applied for stockpiling of the Nipah vaccine.

Dr. Christopher Yallop, Chief Operations and Scientific Officer at Batavia Biosciences elaborates: “We will deploy our High Intensity Process technology in combination with the NevoLine™ production technology (Univercells; Belgium) to develop a manufacturing process, deliver GMP drug product for clinical trials, and transfer the process to a Developing Country Vaccine Manufacturer for stockpiling purposes. We are excited that after years of developing our  highly intensified manufacturing platform, we are now taking the next step to strengthen global health initiatives.”


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