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Myristoylation Probes, Rethought

10:25 EDT 17 May 2019 | Science

The need for good chemical probes continues, and (sadly) so does the use of crappy ones. That’s what I took away from this recent paper from a multicenter team out of London. They’re looking at commonly used probes for inhibition of N-myristoyltransferase (NMT) enzymes, and it’s one of those good-news/bad-news situations. N-myristoylation is another one

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