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Dickkopf-related protein 3 (DKK3) predicts AKI

20:00 EDT 13 Jun 2019 | AAAS

(ERA-EDTA) Acute kidney injury (AKI) is a common complication after cardiac surgery. The severity fluctuates from subclinical AKI, an increase in biochemical markers, to severe AKI requiring dialysis. Furthermore, AKI impacts hospitalization and mortality. AKI is often diagnosed late - therefore the search for reliable biomarkers for its prediction is important. A new study published in 'The Lancet' showed that urinary DKK3 is an indicator of renal tubular cell stress that significantly improves prediction of AKI.

Original Article: Dickkopf-related protein 3 (DKK3) predicts AKI

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