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[Comment] Varicella zoster virus vaccine in patients with haematological malignancies

22:19 EDT 6 Aug 2019 | The Lancet

Reactivated varicella zoster virus disease is a painful and potentially severe infectious complication of immuno-suppression that, for example, can affect patients with cancer.1–3 An effective zoster vaccine has been used in elderly people for several years, but there is a risk for severe side effects in immunocompromised people, and deaths have been reported.4,5 More recently, a subunit vaccine was introduced and has been shown to be effective in the elderly population.6 A randomised trial also showed effectiveness and safety of this vaccine in patients who had undergone autologous stem cell transplantation.

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